Publications


2017
  • Lobanenkov VV, Zentner GE. Discovering a binary CTCF code with a little help from BORIS. Nucleus, in press. PubMed | PDF
  • Policastro RA, Zentner GE. Enzymatic methods for genome-wide profiling of protein binding sites. Brief Funct Genomics, in press. PubMed | PDF
  • Zentner GE, Wade MJ. The promise and peril of CRISPR gene drives. BioEssays 39(10):1700109. PubMed | PDF
  • Grünberg S, Zentner GE. Genome-wide Mapping of Protein-DNA Interactions with ChEC-seq in Saccharomyces cerevisiae. J Vis Exp 124:e55836. PubMed | PDF
  • Kasinathan S, Zentner GE, Xin B, Rohs R, Henikoff S. Correspondence: Reply to 'DNA shape is insufficient to explain binding'. Nat Commun 8:15644. PubMed | PDF
  • Drury DW, Dapper AL, Siniard DJ, Zentner GE, Wade MJ. CRISPR/Cas9 gene drives in genetically variable and nonrandomly mating wild populations. Sci Adv 3(5):e1601910. PubMed | PDF
  • Grünberg S, Zentner GE. Genome-wide characterization of Mediator recruitment, function, and regulation. Transcription 8(3):169-174. PubMed | PDF
  • Rivero-Hinojosa S, Kang S, Lobanenkov VV, Zentner GE. Testis-specific transcriptional regulators selectively occupy BORIS-bound CTCF target regions in mouse male germ cells. Sci Rep 7:41279. PubMed | PDF
2016
  • Grünberg S, Henikoff S, Hahn S, Zentner GE. Mediator binding to UASs is broadly uncoupled from transcription and cooperative with TFIID recruitment to promoters. EMBO J 35(22):2435-2446. PubMed | PDF | GEO
2015
  • Zentner GE, Kasinathan S, Xin B, Rohs R, Henikoff S. ChEC-seq kinetics discriminates transcription factor binding sites by DNA sequence and shape in vivo. Nat Commun 6:8733. PubMed | PDF | GitHub | GEO
  • Zentner GE, Henikoff S. Epigenome editing made easy. Nat Biotechnol 33(5):606-607. PubMed | PDF
  • Orsi GA, Kasinathan S, Zentner GE, Henikoff S, Ahmad K. Mapping Regulatory Factors by Immunoprecipitation from Native Chromatin. Curr Protoc Mol Biol 110:21.31.1-21.31.25. PubMed | PDF
  • Ramachandran S, Zentner GE, Henikoff S. Asymmetric nucleosomes flank promoters in the budding yeast genome. Genome Res 25(3):381-390. PubMed | PDF | GEO

2014
  • Zentner GE, Henikoff S. High-resolution digital profiling of the epigenome. Nat Rev Genet 15(12):814-827. PubMed | PDF
  • Factor DC, Corradin O, Zentner GE, Saiakhova A, Song L, Chenoweth JG, McKay RD, Crawford GE, Scacheri PC, Tesar PJ. Epigenomic Comparison Reveals Activation of "Seed" Enhancers during Transition from Naive to Primed Pluripotency. Cell Stem Cell 14(6):854-863. PubMed | PDF | GEO
  • Weeks LD, Zentner GE, Scacheri PC, Gerson SL. Uracil DNA glycosylase (UNG) loss enhances DNA double strand break formation in human cancer cells exposed to pemetrexed. Cell Death Dis 5:e1045. PubMed | PDF
  • Zentner GE, Balow SA, Scacheri PC. Genomic characterization of the mouse ribosomal DNA locus. G3 4(2):243-254. PubMed | PDF
  • Kasinathan S, Orsi GA, Zentner GE, Ahmad K, Henikoff S. High-resolution mapping of transcription factor binding sites on native chromatin. Nat Methods 11(2):203-209. PubMed | PDF | GEO

2013
  • Zentner GE, Henikoff S. Mot1 redistributes TBP from TATA-containing to TATA-less promoters. Mol Cell Biol 33(24):4996-5004. PubMed | PDF | GEO
  • Balow SA, Pierce LX, Zentner GE, Davis S, Sabaawy HE, McDermott BM Jr, Scacheri PC. Knockdown of fbxl/kdm2bb rescues chd7 morphant phenotypes in a zebrafish model of CHARGE syndrome. Dev Biol 382(1):57-69. PubMed | PDF
  • Zentner GE, Tsukiyama T, Henikoff S. ISWI and CHD chromatin remodelers bind promoters but act in gene bodies. PLoS Genet 9(2):e1003317. PubMed | PDF | GEO
  • Zentner GE, Henikoff S. Regulation of nucleosome dynamics by histone modifications. Nat Struct Mol Biol 20(3):259-266. PubMed | PDF

2012
  • Zentner GE, Henikoff S. Surveying the epigenomic landscape, one base at a time. Genome Biol 13(10):250. PubMed | PDF
  • Zentner GE, Scacheri PC. The chromatin fingerprint of gene enhancer elements. J Biol Chem 287(37):30888-30896. PubMed | PDF

2011
  • Zentner GE, Tesar PJ, Scacheri PC. Epigenetic signatures distinguish multiple classes of enhancers with distinct cellular functions. Genome Res 21(8):1273-1283. PubMed | PDF
  • Yazbek SN, Buchner DA, Geisinger JA, Burrage LC, Spiezio SH, Zentner GE, Hsieh C-W, Scacheri PC, Croniger CM, Nadeau JH. Deep congenic analysis identifies many strong, context-dependent QTLs, one of which, Slc35b4, regulates obesity and glucose homeostasis. Genome Res 21(7):1065-1073. PubMed | PDF
  • Zentner GE, Saiakhova A, Manaenkov P, Adams MD, Scacheri PC. Integrative genomic analysis of human ribosomal DNA. Nucleic Acids Res 39(12):4949-4960. PubMed | PDF | SRA

2010
  • Tran T, Jarrell A, Zentner GE, Welsh A, Brownell I, Scacheri PC, Atit R. Role of canonical Wnt signaling/beta-catenin via Dermo1 in cranial dermal cell development. Development 137(23):3973-3984. PubMed | PDF
  • Zentner GE, Hurd EA, Schnetz MP, Handoko L, Wang C, Wang Z, Wei C, Tesar PJ, Hatzoglou M, Martin DM, Scacheri PC. CHD7 functions in the nucleolus as a positive regulator of ribosomal RNA biogenesis. Hum Mol Genet 19(18):3491-3501. PubMed | PDF
  • Zentner GE, Layman WS, Martin DM, Scacheri PC. Molecular and phenotypic aspects of CHD7 mutation in CHARGE syndrome. Am J Med Genet A 152A(3):674-686. PubMed | PDF

2009
  • Schnetz MP, Bartels CF, Shastri K, Balasubramanian D, Zentner GE, Balaji R, Song L, Zhang X, Wang Z, LaFramboise T, Crawford GE, Scacheri PC. Genomic distribution of CHD7 on chromatin tracks H3K4 methylation patterns. Genome Res 19(4):590-601. PubMed | PDF | GEO