Ph.D., University of Essex, 2008
Postdoctoral Fellow, University of Aachen, 2008-2009
Postdoctoral Fellow, Karolinska Institute, 2009-2011
Postdoctoral Fellow, NIAID, 2011-2016
I grew up in South Korea and obtained my Ph.D. in Cell/Molecular Biology at the University of Essex, United Kingdom. During my Ph.D. studies, I found a direct link between the insulator-binding protein CTCF and RNA Polymerase II, suggesting that CTCF may recruit Pol II to a subpopulation of CTCF binding sites. I then spent time at the University of Aachen, Germany studying the role of LPA receptors in initiating CXCL12-dependent vascular repair by smooth muscle progenitor cells. I then moved to Karolinska Institutes, Sweden to explore the contention that CTCF functions and its binding sites within the H19 ICR are functionally diverse and organize context-dependent higher order chromatin conformations. Recently, at the National Institute of Allergy and Infectious Diseases, I characterized CTCF and its partner cohesin during the G2/M phase of the cell cycle.
Chromatin structure and other epigenetic factors play crucial roles in gene expression, selectively enhancing or silencing transcriptional activities speciﬁc to various cell types. My current research focuses on understanding gene regulation by CTCF and its paralog BORIS through interactions with the general transcription machinery and other factors with the long-term goal of understanding the interplay between CTCF/BORIS, cell type-specific transcription factors, and chromatin structure in gene regulation.
When not in the lab you will find me spending time with my family, exploring nature, going to concerts/films, watching baseball, and playing tennis.